One-pot three component synthesis of heteroarylated arylacetates via VNSAr-SN reaction using N-methylpyrrolidone as general solvent.
نویسندگان
چکیده
An efficient three component one-pot method was developed to assemble 2-heteroaryl-2-aryl acetates via VNS(Ar)-S(N)Ar and VNS(Ar)-S(N) reaction by using N-methylpyrrolidone (NMP) as general solvent.
منابع مشابه
A Simple and Efficient One-Pot Synthesis of 1,4-Dihydropyridine and Polyhydroquinoline Derivatives Using Phosphosulfonic Acid as a Heterogeneous Catalyst under Solvent-Free Conditions
Phosphosulfonic acid (PSA) was found to be an efficient catalyst for the one-pot three-component Hantzsch condensation reaction of arylaldehydes, ethylacetoacetate and ammonium acetate to afford the corresponding 1,4-dihydropyridine and polyhydroquinoline derivatives in high yields. PSA was also applied for the one-pot preparation of polyhydroquinolines via four-component reaction of a...
متن کاملApplication of Non-Corrosive Acids in Three-Component, One-Pot Synthesis of Commercial Coumarin Dye
The efficiency of HZSM-5 Zeolite, tungestophosphoric acid (H3PW12O40) and tungestosililic acid (H4O40SiW12) were investigated in three-component, one-pot synthesis of coumarin dyes. These green and noncorrosive acids were highly efficient in synthesis of some coumarin dyes in excellent yield during concurrent formation of coumarin and benzimidazole or benzoxazole heterocycles (e.g. C. I. disper...
متن کاملOne-pot three-component synthesis of dialkyl 3-(alkylamino)-1-aryl-1H-pyrazole-4,5-dicarboxylates using α-Fe2O3 nanoparticles and phenylisocyanate in solvent-free conditions
This work described a simple and efficient synthesis of dialkyl 3-(alkylamino)-1-aryl-1H-pyrazole-4,5-dicarboxylates via a three component reaction between arylhydrazine, alkylisocyanid and dialkylacetylenedicarboxylates in the presence of phenylisocyanate and α-Fe2O3 nanoparticles. Eco friendly, solvent-free conditions, excellent yields, and short reaction times, inexpensive and readily availa...
متن کاملOne-pot three component synthesis of 2-amino-4H-chromenes under green and high efficient conditions
A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
متن کاملOne-pot three component synthesis of 2-amino-4H-chromenes under green and high efficient conditions
A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 6 7 شماره
صفحات -
تاریخ انتشار 2008